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Eldepryl is used in combination with levodopa or levodopa and carbidopa combination to treat parkinson s disease sometimes called shaking palsy or paralysis agitans .

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Information about Eldepryl.

Eldepryl may impair your thinking or reactionsSome people taking this medicine have fallen asleep during normal daytime activities such as workingtalkingeatingor drivingYou may fall asleep suddenlyeven after feeling alertBe careful if you drive or do anything that requires you to be alert.

The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotoninExamples include street drugs such as MDMAecstasyStJohn’s wortdextromethorphancertain antidepressantsincluding SSRIs such as fluoxetine/paroxetineSNRIs such as duloxetine/venlafaxineTCAs such as amitriptyline/doxepincertain narcotic medicationssuch as meperidinemethadonepentazocinepropoxyphenetramadoltapentadolamong othersThe risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Selegiline should not be used in combination with sympathomimeticssee section 4.5

For the reasons stated abovepatients and providers are advised to monitor for melanomas frequently and on a regular basis when using ELDEPRYL for any indicationIdeallyperiodic skin examinations should be performed by appropriately qualified individualse.gdermatologists

Serious reactions with signs and symptoms that may include diaphoresisflushingataxiahyperthermiahyper/hypotensionseizurespalpitationdizziness and mental changes that include agitationconfusion and hallucinations progressing to delirium and coma have been reported in some patients receiving a combination of selegiline and fluoxetineSimilar experience has been reported in patients receiving selegiline and two other serotonin reuptake inhibitorssertraline and paroxetineThere is a potential risk of interaction with fluvoxamine and venlafaxine.

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eldepryl is used as a treatment for parkinson s disease in its early stage as well as for senile dementia and depression.

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